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    首頁 > 產(chǎn)品中心 > 抗體 > 病毒類抗體 > Biotin-conjugated anti-Dxd mAb

    Biotin-conjugated anti-Dxd mAb

    產(chǎn)品貨號ALZP-18020B
    產(chǎn)品規(guī)格25ug
    目錄價(jià)格 2070.00
    产品信息
    特點(diǎn)
    特性 識別標(biāo)簽:DXD,BIOTIN 應(yīng)用:Elisa/WB
    優(yōu)勢 另有大包裝100ug和1ML出售
    產(chǎn)品詳情

    Biotin-conjugated anti-Dxd mAb

    Background

    Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor. Dxd is cytotoxic to human cancer

    cell lines of KPL-4, NCI-N87, SK-BR-3, and MDA-MB-468 with IC50s of 1.43 nM-4.07 nM, but the control

    IgG-ADC (Dxd is the payload) shows no inhibition on the four cell lines (with HER2 expression).

    Biotin-anti-DXD-antibody is a conjugation product of Biotin and anti-DXD-antibody. It can be used in PK, PD

    analysis and ELISA.

    Specificity: Specifically recognizes the target-DXD

    Source: Mouse, Monoclonal Clone #13

    Isotype: IgG1

    Conjugation: Biotin

    Concentration: 1.0 mg/ml

    Tested applications: ELISA

    Recommended dilution: 1:1000 - 1:5000(optimal dilutions should be determined by the end use.)

    Storage Buffer: PBS Buffer, pH7.4

    Storage: Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Stable for 2

    years from date of receipt. Aliquot to avoid repeated freezing and thawing.

    * Please note: FOR RESEARCH USE ONLY

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